Showing posts with label Hot News. Show all posts
Showing posts with label Hot News. Show all posts

Monday, July 5, 2010

Hyderabad Life Sciences BSc/MSc Trainee/Freshers Jobs @ Alcove Technologies

Alcove Technologies
401, Balaji Residency, Hitec-city Main Road
Near Hotel Kasani GR, Madhapur
Hyderabad – 500 081

Alcove Life Sciences provides its offshore project services in Bioinformatics, Drug discovery, Genomics, Pharmacogenomics, Cheminformatics, Molecular biology, Clinical informatics, Biostatistics and other Information technology services to worldwide corporates and research organizations.

Alcove technologies looking to expand its operations, has a few openings for Trainees/freshers.

Intern/Trainee - Biotech

Experience Requirement: < 1 Year To 2 Years

Education:
Graduate Degree
Post Graduate Degree

Sunday, July 4, 2010

Men ‘like women with small feet’

Men prefer women with small feet — though they might not be aware of it, says a new study.
Jeremy Atkinson, an evolutionary psychologist at the University at Albany, New York, and his colleague Michelle Rowe measured hand length, foot length, thigh length and hip width on 60 white female college students, then adjusted each measurement to account for individual differences in overall height.


For each of 16 body-part measurements, they selected the eight women with the shortest lengths and the eight with the longest, and constructed morphs of their faces.

These morphs were then rated for attractiveness by 77 heterosexual male students, reports New Scientist.

The researchers found that men were three-and-a-half times as likely to pick the short-footed morph as more attractive, and almost 10 times as likely to say it was more feminine.

Similarly, they were more than 11 times as likely to pick the narrow-hipped morph as more attractive, and eight times as likely to choose the long-thighed morph.

Atkinson believes that men find these features attractive because they serve as markers of a healthy childhood. Biologists know that stress and poor nutrition during foetal development and puberty can affect sex hormone levels and cause earlier puberty.

This can leave such women relatively short and stout, while those with a more benign childhood continue growing for longer, and attain a slenderer, more stereotypically feminine face and body, which most men find more attractive.

The research was reported at a meeting of the Human Behavior and Evolution Society in Eugene, Oregon.

World's First Flying Car Cleared for Take Off

Soon, it will be traffic jams in the skies above
Man has always dreamed to take to the air and from time to time, in different stages, this dream was accomplished, first by weather balloons, then by airplanes, then by rockets and now by a flying car. The Terrafugia Transition is a car that can fly, well, not like the one in the movie The Absent Minded Professor , but with wings like a normal airplane.


US Federal Air Authority have given the car-plane a special weight exemption, paving way for the mass production. This is an important thing to note because it is usually difficult to obtain a street-legal car manufacturing license in the US due to higher safety measures, and the Terrafugia Transition seems to have managed to get it.

The Terrafugia Transition will set you back by $195500, while the company is asking for $10,000 deposit up front. Once airborne, the speed of the car-plane powered by 100 hp Rotax 912S engine is expected to be around 115 mph with a payload of around 430 lbs. The first finished vehicle is expected to be delivered in late 2011.

Monday, June 21, 2010

How DNA Is Copied Onto RNA Revealed Through Three-Dimensional Transcription Film

ScienceDaily (June 19, 2010) — Gene expression takes place in two stages: the transcription of DNA to RNA by an enzyme called RNA polymerase, , followed by the translation of this RNA into proteins, whose behaviour affects the characteristics of each individual.

Transcription: a mechanism controlled in time and space
Transcription involves about fifty regulatory molecules that interact with each other to begin reading the gene at the right place and the right time. The slightest irregularity of one of these molecules disturbs the transcription. An understanding of the initiation and regulation mechanisms is essential in order to understand gene expression. The structural biology researchers at IGBMC are studying molecular structures to gain a better understanding of how they function. Patrick Schultz's team is particularly focusing on the architecture of the molecules involved in transcription and attempting to decode the mechanisms of their interactions.
An 'image-by-image' analysis
An analysis of the transcription complexes by electron cryomicroscopy allows a molecule to be observed in a hydrated state close to its natural state. Each photograph, taken using a microscope, shows thousands of specimens of the same molecule from different angles and at different instants in their reaction cycle. The statistical analysis of these images performed by Patrick Schultz's team revealed different conformations in three dimensions, which correspond to different stages of transcription initiation. 'We performed image-by-image sequencing and made a film of the initial stages of transcription,' says Schultz.
The factor TFIID, the main player in the transcription process
Patrick Schultz's team is interested in a complex protein that acts as an assembly platform in the initiation phase of transcription: the factor TFIID. Through interaction with the activator Rap1, bound upstream from the gene to be transcribed, it is attracted to the DNA and binds onto it. Combined with another factor, TFIIA, it changes conformation and allows the RNA polymerase to initiate transcription. The original aspect of this mechanism is based on the formation of a DNA loop, which allows the RNA polymerase to be positioned exactly at the start of the sequence of the gene to be transcribed.
The structure of the transcription factor TFIID obtained after image analysis is represented in yellow on an electron cryomicroscopy image background, showing the frozen hydrated molecules in dark grey. The transcription activator Rap1 (red) interacts with the factor TFIIA (blue) and contributes to forming a DNA loop (green).
What is electron cryomicroscopy?
The biological molecules in living organisms exist in an aqueous environment, which must be preserved whilst observing the molecules. In order to be 'seen', however, molecules must be placed in an electron microscope, which operates in a vacuum and dehydrates the sample. The solution, developed in the 1980s, is to use refrigeration to keep the specimen hydrated and to examine it by electron cryomicroscopy. A very thin film (approximately 100 nm, or one ten-thousandth of a millimetre thick) of the suspension containing the sample to be analysed must be created in order to be transparent to electrons. (Thin film shown in light blue in Figure A.) This film is cooled very rapidly (at a rate of approximately 10,000°C per second) by plunging it into liquid ethane cooled to -170°C. This freezing speed prevents the formation of ice crystals, and the sample (yellow in Figure A) is trapped in a layer of vitrified water. The cold chain must be maintained throughout the observation period using a cold plate. The molecules (dark grey in Figure B) are hydrated and observed without contrast agent.

Saturday, May 1, 2010

Nokia India To Launch Stunning N8 By Diwali 2010

If you have ever thought that Nokia has gone into the shadows equipped with a host of smartphone talents then you are wrong, because Nokia unveils N8, one of the best Super phone in N-Series probably.
This is the first device to be powered by the brand new Symbian 3 platform, the Nokia N8 will launch with a new super breed of camera that promises to capture photos and video beyond your imagination.
The biggest plus in the Nokia N8 is its 12-megapixel camera with Carl Zeiss optics and Xenon flash.
It also features a substantially BIGGER sensor than any ever used in any other Nokia device – even bigger than many found in dedicated cameras.The N8 is also the first Nokia device to support HD Video recording And also allows you to edit them with a smart built-in editing suite on the device.
This super phone also supports Dolby Digital Plus surround sound and users can connect it to their home theatre system.There’s also a HDMI connector allowing you to hook the smartphone to your HD TV and share your media with friends and family with a very high level of clarity.
The Nokia N8 also doubles as a portable entertainment centre, allowing you to watch HD quality video with Dolby Digital Plus surround sound and hook into a dedicated Web TV application for access to news and entertainment on the move.Nokia N8 also exceeds your imagination in the space constraints as it has 16GB of built-in storage and is expandable up to 48GB with a micro SD card.
Joining the social messaging Bandwagon fold with the likes of the latest Eseries and Cseries devices, N8 enters the fray with LIVE Twitter and Facebook updates direct to your homescreen. Comment, read and send messages, update your status and share your location and photos with just a touch.Embracing the likes of location based services, the N8 is very location-savvy and comes with FREE global Ovi Maps walk and drive navigation with support in more than 70 countries worldwide for LIFETIME.
Nokia N8 is carved from a single piece of anodised aluminium and looks glorious decked in one of five eye-catching colours, The N8 will be available in SELECT markets during the third quarter of 2010 and in India by Diwali. It is estimated to be priced at around the EUR 360 (Rs. 22,000) excluding taxes or subsidies in Countries other than India. Also, it would be outright foolishness to expect this phone to be priced below the 25k mark in India, that’s something Nokia has learnt more from its brother companies like Apple :) .

Thursday, April 22, 2010

Nokia N800 Internet Tablet

Remember the Nokia 770 Tablet ? Well, if not heres the successor for it. The Nokia N800 is latest addition from Nokia in the Internet Tablet market. The N800 comes with a VGA camera which can mainly be used as a Webcam. It has a 4.13 inch screen with stereo speakers.


The Nokia N800 comes with Wi-Fi 802.11 b/g and Bluetooth as well. You can't say that the N800 is too much better than the 770 in looks, infact the N800 is much wider than the N770. One thing that the N800 has which the N770 does not is the extra SD card slot. The N770 had a RS-MMC card slot so this is just a minor update.

We still don't know the difference in the processor and RAM specs but if there isn't too much difference in that I don't know why did they bother to bring in the update at all. The downside to both these internet tablets is the lack of GSM/CDMA compatibility. Why can't they just add the mobile feature after doing so much hard work!

Monday, March 15, 2010

Internet nominated for '2010 Nobel Peace Prize'


It's official. The Internet, which has virtually revolutionised the world, has been nominated for the '2010 Nobel Peace Prize'.

The Internet was proposed by the Italian edition of the popular Wired magazine for promoting "dialogue, debate and consensus through communication" as well as democracy, the media reported.

Premier endorsers of Internet for Nobel Peace Prize nomination include 2003 Nobel laureate Shirin Ebadi and famous Italian surgeon, known for his contributions to breast cancer treatments, Umberto Veronesi.

Wired Italy has also launched a dedicated campaign, 'Internet for Peace', which will carry on till September 2010, featuring different stories and experiences of those who with the web have tried to do something concrete to promote peace and harmony in the world.

"We have to look at the Internet as a huge community where men and women from all over the world and with very different religious views can communicate and sympathise,
spreading a new culture centred on collaboration and sharing of knowledge that breaks all barriers.

"For this reason, the Internet can be considered the first weapon of mass construction, which we can deploy to destroy hate and conflict and propagate peace and democracy.

"What happened in Iran after the latest election and the role the web played in spreading information that would otherwise have been censored, are only the newest examples of how the Internet can become a weapon of global hope," Riccardo

Thursday, March 11, 2010

Get free wireless internet access

This post explains about how can you get a free wireless internet access. If you live in a very big apartment chances are, people have internet access and some of them even have wireless connection. So it is possible for you to connect and use their wireless internet on your mobile devices live laptops, mobile phones and even i-pod touch.


I'm not talking a techie or geeky stuff, there is a software called Easy Wifi Radar which does it easily.

Download this software from here http://www.makayama.com/easywifiradar.html. After you download just go through the easy installation. Then open the software and let it do the work automatically. When you get a connection just open your internet browser. Go ahead and download this software.

Enjoy!!

Guruji.com Music Search - The easiest and fastest way to your favorite song

1) Have you ever tried looking for your favorite song and gotten disappointed?


2) Have you ever complained about not having a one stop shop for online music?

3) Did you ever wish a search engine solved these problems for you, at least for Indian music?

If the answer to at least one question above is yes, read on.

Guruji Music Search – Guruji Music Search is a one stop shop for all Music lovers searching for Music on the Web. Our Music Index (enriched by songs crawled from all over from the web) has songs ranging from 1932 till 2008, across languages. Guruji Music Search is an attempt to allow users to search for songs in the fastest and easiest way possible. You can search for a song by the song’s words, singers, movie/album, actors, music directors and so on…

One can use the “usual” queries (like by Movie or by Song) to search for the song –


Taare Zameen Par

Rang De Basanti

Or go for some specific queries like –

Dilip+Kumar+Laxmikant+Pyarelal+1986 (Songs featuring Dilip Kumar

with music by Laxmikant Pyarelal and released in 1986)

Couldn’t guess the movie of the song? – Karma.

You can also refine your results on parameters like – Language, Time and whether the word occurs in Song, Movie/Album Title, Singer, Actor and so on.

For example the search query “Kishore Kumar”, the user can refine for –

1. Languages – Hindi, Bengali, Marathi (Languages in which Kishore Kumar has sung)

2. Time – 1971-1975, 1981-1985, 1976-1980, 2006-2008, 1956-1960

3. Category – Kishore Kumar as Singer, Actor, Composer

Do try it out and let us know what you thought.

Guruji Music Search, coz everybody needs a little music in life!

Also available in all South Indian languages including Telugu......So,What are you waiting for?.........Get into music.guruji.com

2 Indian women in Forbes ultra-rich list

Two Indian women including Savitri Jindal and Indu Jain have been named among the list of world's top billionaires compiled by the US magazine Forbes.


Jindal with a net worth of $12.2 billion has been ranked at 44th place in the global list, while Bennett, Coleman & Co's chairperson Indu Jain at $2.8 billion comes at 354th rank.

Jindal, the non-executive chairperson of, steel and power conglomerate, OP Jindal Group, is the fifth richest woman in the world.

Retail chain major Wal-Mart's Christy Walton is world's richest woman with a net worth of $22.5 billion, placed at the 12th position in the overall list led by Mexican billionaire Carlos Slim, with a fortune of $53.5 billion.

Walmart's Alice Walton follows as the second richest women in the list with a networth of $20.6 billion at the 16th place.

Walton is followed by L'Oreal heiress Liliane Bettencourt (with networth of $20 billion), Swedish packaging giant Tetra Laval's Birgit Rausing & family ($13 billion), and Savitri Jindal ($12.2 billion).

The Forbes list of 1,011 billionaires includes 89 women from across the globe. From India, there are just two women and 48 men.

Indian industrialist Mukesh Ambani has been named as the richest Indian and fourth richest person globally with a networth of $29 billion.

Forbes rich list: India's wealthiest people

Traditionally dominated by Americans and Europeans, the 2010 Forbes list of world's billionaires released on Wednesday has thrown up many surprises including Mexican telecoms tycoon Carlos Slim grabbing the top slot.


According to Forbes, Asian billionaires increased their wealth as the region’s rich expanded their fortunes at the world’s quickest pace in the past year. Forbes said the list reflect the increasing presence of developing nations.

Reliance Industries (RIL) Chairman Mukesh Ambani and steel czar Lakshmi Mittal have figured in the top 10 on the 2010 Forbes list of world's billionaires.

With China and India leading the way, the number of Asian billionaires increased to 234 from 130 a year earlier, Forbes said.

Following is the Forbes list of top 25 richest people in India.


Rank -- Name -- Net Worth (in $ bln)

4 Mukesh Ambani $29.0

5 Lakshmi Mittal $28.7

28 Azim Premji $17.0

36 Anil Ambani $13.7

40 Shashi & Ravi Ruia $13

44 Savitri Jindal $12.2

74 K P Singh $9.0

86 Kumar Birla $7.9

87 Sunil Mittal $7.8

113 Anil Agarwal $6.4

148 Adi Godrej &family $5.2

167 Gautam Adani $4.8

173 Dilip Shanghvi $4.6

201 Shiv Nadar $4.2

297 G M Rao $3.2

297 Malvinder & Shivinder Singh $3.2

316 Uday Kotak $3.0

342 Kalanithi Maran $2.9

354 Subhash Chandra $2.8

354 Micky Jagtiani $2.8

354 Indu Jain $2.8

463 Sudhir & Samir Mehta $2.1

488 Yusuf Hamid & family $2.0

488 Cyrus Poonawalla $2.0

488 Rajan Raheja $2.0.

Forbes releases billionaires ’10 list

Forbes has released its 2010 list of Billionaires. There at least two Indians in the top five list and the richest man is no longer Bill Gates.

The veterans Bill Gates and Warren Buffet have made way for Mexican telecom tycoon, Carlos Slim Helu, at the top spot with a networth of $53.5 billion, pushing Gates and Buffet to runner up positions at rank 2 and 3 respectively.


Cashing in at 4 and 5 are none other than fellow Indians, Mukesh Ambani and Laxmi Mittal.

Mukesh Ambani has bagged the 4th spot with a networth of a massive $29 billion as compared to last years 7th place and $19.5 billion dollar networth.

Steel tycoon Laxmi Mittal has also moved up from being ranked 8th to round off this years top 5 with networth of $28.7 billion as against last years $19.3 billion.

India has prominently featured in the list this year as compared to last with a total of six Indians in the top 50 as compared to only the Ambani brothers and Laxmi Mittal being listed last year.

India has also clocked a massive $113.6 billion put together, making the $48.8 billion networth of the three individuals last year look like a measly sum.

Azim Premji has joined the elite 50 in the 28th position with $17 billion. But Mukesh's younger brother Anil Ambani slipped two places down from the 34th rank last year to 36th this year with his networth standing at $13.7 billion.

Essar brothers, Shashi and Ravi Ruia come in at 40th with $13 billion and rounding up India's standing in the top fifty is Savitri Jindal with $12 billion networth.

With the India growth story back on track and Indian business making its presence felt in the global arena, the Forbes listing reflects the rise and rise of the Asian tiger

Bill Gates No Longer World's Richest Man

Carlos Slim Helu takes No. 1 spot on Forbes World's Billionaires list as a record 164 10-figure titans return to the ranking amid the global economic recovery.


For the third time in three years, the world has a new richest man.

Riding surging prices of his various telecom holdings, including giant mobile outfit America Movil ( AMX - news - people ), Mexican tycoon Carlos Slim Helu has beaten out Americans Bill Gates and Warren Buffett to become the wealthiest person on earth and nab the top spot on the 2010 Forbes list of the World's Billionaires.

Slim's fortune has swelled to an estimated $53.5 billion, up $18.5 billion in 12 months. Shares of America Movil, of which Slim owns a $23 billion stake, were up 35% in a year.

That massive hoard of scratch puts him ahead of Microsoft ( MSFT - news - people ) cofounder Bill Gates, who had held the title of world's richest 14 of the past 15 years.


Gates, now worth $53 billion, is ranked second in the world. He is up $13 billion from a year ago as shares of Microsoft rose 50% in 12 months. Gates' holdings in his personal investment vehicle Cascade ( CAE - news - people ) also soared with the rest of the markets.

Buffett's fortune jumped $10 billion to $47 billion on rising shares of Berkshire Hathaway ( BRK - news - people ). He ranks third.

The Oracle of Omaha shrewdly invested $5 billion in Goldman Sachs ( GS - news - people ) and $3 billion in General Electric ( GE - news - people ) amid the 2008 market collapse. He also recently acquired railroad giant Burlington Northern Santa Fe ( BNI - news - people ) for $26 billion.

In his annual shareholder letter Buffett wrote, "We've put a lot of money to work during the chaos of the last two years. When it's raining gold, reach for a bucket, not a thimble."

Many plutocrats did just that. Indeed, last year's wealth wasteland has become a billionaire bonanza. Most of the richest people on the planet have seen their fortunes soar in the past year.

Wednesday, March 10, 2010

Notable People Who Dropped Out of School

Everyone knows how important it is to stay in school, get a good education, and graduate with a diploma. But it may be hard to stay focused after reading about the success of these famous dropouts. Hard work, drive, natural talent, and sheer luck helped them overcome their lack of education, but many still returned to school later in life.

In this article, you will learn about notable people including inventors, politicians, and entertainers who dropped out of school before their rise to fame.

1. Thomas Edison Thomas Edison is probably the most famous and productive inventor of all time, with more than 1,000 patents in his name, including the electric light bulb, phonograph, and motion picture camera. He became a self-made multimillionaire and won a Congressional Gold Medal. Edison got a late start in his schooling following an illness, and, as a result, his mind often wandered, prompting one of his teachers to call him "addled." He dropped out after only three months of formal education. Luckily, his mother had been a schoolteacher in Canada and home-schooled young Edison.

2. Benjamin Franklin

Benjamin Franklin wore many hats: politician, diplomat, author, printer, publisher, scientist, inventor, founding father, and coauthor and cosigner of the Declaration of Independence. One thing he was not was a high school graduate. Franklin was the fifteenth child and youngest son in a family of 20. He spent two years at the Boston Latin School before dropping out at age ten and going to work for his father, and then his brother, as a printer.

3. Bill Gates


Bill Gates is a co-founder of the software giant Microsoft and has been ranked the richest person in the world for a number of years. Gates dropped out of Harvard in his junior year after reading an article about the Altair microcomputer in Popular Electronics magazine. He and his friend Paul Allen formed Micro Soft (later changed to Microsoft) to write software for the Altair.

4. Albert Einstein


Although he was named Time magazine's "Man of the Century," Albert Einstein was not an "Einstein" in school. The Nobel Prize-winning physicist, famous for his theory of relativity and contributions to quantum theory and statistical mechanics, dropped out of high school at age 15. Deciding to continue his education a year later, Einstein took the entrance exam to the prestigious Swiss Federal Institute of Technology, but failed. He returned to high school, got his diploma, and then passed the university's entrance exam on his second attempt.


5. John D. Rockefeller


Two months before his high school graduation, history's first recorded billionaire, John D. Rockefeller, Sr., dropped out to take business courses at Folsom Mercantile College. He founded the Standard Oil Company in 1870, made his billions before the company was broken up by the government for being a monopoly, and spent his last 40 years giving away his riches, primarily to causes related to health and education. Ironically, this high school dropout helped millions get a good education.

6. Walt Disney


In 1918, while still in high school, future Oscar-winning film producer and theme park pioneer Walt Disney began taking night courses at the Academy of Fine Arts in Chicago. Disney dropped out of high school at age 16 to join the army, but because he was too young to enlist, he joined the Red Cross with a forged birth certificate instead. Disney was sent to France where he drove an ambulance that was covered from top to bottom with cartoons that eventually became his film characters. After becoming the multimillionaire founder of the Walt Disney Company and winning the Presidential Medal of Freedom, Disney received an honorary high school diploma at age 58.

7. Richard Branson


Britain's Sir Richard Branson is a self-made billionaire businessman. He founded Virgin Atlantic Airways, Virgin Records, Virgin Mobile, and most recently, a space tourism company to provide suborbital trips into space for anyone who can afford them. Suffering from dyslexia, Branson was a poor student, so he quit school at age 16 and moved to London, where he began his first successful entrepreneurial activity, publishing Student magazine.

Thursday, March 4, 2010

India among top 5 government funders of neglected diseases

India along with Brazil are now in the top 5 government funders of neglected disease R&D and are taking the lead on diseases like leprosy and dengue fever. An annual survey of investment into neglected disease R&D released, shows that nearly $2.96 billion was spent on making new products for neglected diseases in 2008. A key finding of the G-FINDER survey was that, for some diseases, traditional donor funding is being replaced by investment from pharmaceutical companies and Innovative Developing Countries (IDCs) such as Brazil, India and South Africa. Where there is no profitable market, as with many of the diseases that affect sub Saharan Africa, R&D remains heavily reliant on traditional donor and philanthropic funding


“These are tough economic times but, for the first time, we are seeing that for some neglected diseases the traditional reliance on charitable funding and donor aid is being replaced by a market and domestically driven R&D,” said report author, Dr Mary Moran of The George Institute for International Health. “This is good news for new medicines and diagnostics in India, Brazil and South Africa, but not for most of sub Saharan Africa where there is still no market and they will have to rely on donors and philanthropists for some time yet,” she added.

This trend reflects the growing research strength and pharmaceutical markets of India and Brazil, in particular, as well as high local incidence of diseases such as leprosy and dengue. The downside of this trend is that diseases of Africa continue to rely on donors, who still provide more than 85 percent of funds for Buruli ulcer, trachoma, kinetoplastid diseases like sleeping sickness and many helminth infections.


Report Findings


The G-FINDER report shows that in 2008 Innovative Developing Countries (IDC`s) like India, Brazil and South Africa and pharmaceutical companies funded:

1.Nearly 60 percent of R&D for pneumonia and meningitis


2.More than half (51 percent) of leprosy R&D (Brazil and India have the largest number of new leprosy cases per year in the world)


3.Nearly half (46 percent) of R&D for new dengue products (the Americas, particularly Brazil, along with Asia, have the highest global prevalence of dengue)


4.Around 20 percent of funding for new treatments and vaccines for diarrhoeal illnesses, TB and malaria (which occur worldwide)

“The G-Finder survey report has put India as the 5th largest public funder of neglected diseases, and ICMR provides 60 percent of the funds. Visceral leishmaniasis and leprosy are amongst most neglected diseases, and we must further improve our funding for research to find new tools to combat them,” said Dr V M Katoch, Secretary, Department of Health Research, and Director-General, Indian Council of Medical Research, New Delhi.


Other Key Findings


•Global funding for neglected disease R&D ground to a standstill in 2008, with funding cuts or freezes across the board including a $26.3 million decrease in funding from High-Income Countries (HICs)

•This injection of additional funds led to a net increase of $100.1m (3.9 percent) in global neglected disease R&D investment in 2008.

•Two organizations provided nearly 60 percent of global funding in this area in 2008: the US National Institutes of Health ($1.1 billion, 36.5 percent) and the Gates Foundation ($617 million, 20.9 percent).

•The pharmaceutical industry was collectively the third largest global investor, with companies providing one-eighth ($365 million, 12.4 percent) of global funding for neglected disease R&D.

"This G-Finder report confirms the welcome news that an increasing number of Pharma companies are allocating R+D resources to the neglected diseases surveyed. Although no major financial returns can be expected with medicines for many of these diseases in the foreseeable future, there is a growing sense of responsibility for underprivileged patients and reputational aspects,which are helping to improve the lives of patients”, said Prof Paul L Herrling, Head of Corporate Research for Novartis International.

Budget 2010 to boost research

Bangalore, Mar 03, 2010: Over the years, the finance ministry has given the life sciences industry due emphasis in budget. With India figuring low on various healthcare counts, increased allocation in healthcare shows the government’s commitment to tackle the situation.



Through the budget 2010, Finance Minister Pranab Mukherjee has proposed to extend the scope of weighted deduction on expenditure incurred on in-house Research and Development to 200 percent from 150 percent, to be effective upto 2012. Mukherjee has also proposed to increase the weighted deduction on payments made to national laboratories and research organizations for scientific research from 125 percent to 175 percent. But at the same time increase in MAT to 18 percent from 15 percent and input duty on raw materials from 8 to 10 percent has made the industry unhappy.


Reacting to the budget Sanjay Nagrath, Chief Financial Officer, Intas Biopharmaceuticals says, “It is a welcome move from Finance Minister to raise weighted deduction on in–house R&D expenditure from 150 percent to 200 percent and weighted deduction on payment made to national laboratories research association, colleges, and other institutions for scientific research is increased to 175 percent from 125 percent. Reduction in excise duty on goods covered under the Medicinal and Toilet preparation Act from 16 percent to 10 percent is also a positive move.”


"GST (Goods & Services Tax) implementation from April 2011 was expected however it is important that the government ensures timely implementation”, he said.


Commenting on the weighted R&D deduction, Satish Reddy, Managing Director and COO, Dr. Reddy’s Laboratories said, “From the pharmaceutical sector perspective, which is an innovation driven industry, increase in weighted deduction on expenditure incurred on in-house R&D is a positive and encouraging move.


“The Government’s commitment to ensure continued growth of Special Economic Zones augurs well for industrial development. While we await the fine print on specifics and implementation proposal, the aim to implement GST and DTC by April 2011 is a welcome move, he adds.


Praveen Gupta, VP-Business Development, Premas Biotech echoed the same point,“The increase in allocation of fundings for biotech R&D has been a great step which will boost the research into some major areas. But he lamented at the fact that nothing has been done on the import duty which according to him is a major bottleneck in the competition at global scale.


In addition, the industry is almost unanimous in claiming that the benefits, which would accrue from this incentive, would be more than neutralized by the increase in MAT to 18 percent from 15 percent . The industry had requested that the last year's MAT hike from 10 percent to 15 percent be reversed in this budget, however the industry feels disappointed as this was not done.


“The increase in the MAT rate is a negative step for industry as it will increase tax burden on the MAT paying companies,” says Sanjay of Intas Biopharmaceuticals.


Satish opines, “Reduction in corporate surcharge will provide marginal relief while the MAT rate increase, which is likely to balance out the benefits, could have been avoided.”


The 2010 budget may prove to be a mixed bag for life sciences sector as well as patients, with prices of medicines going up marginally by 1-2 percent, while concessions given to medical, surgical, dental equipment and ortho-paedic implants leading to reduction in prices.


Industry feels that prices may be increased on account of higher raw material costs due to the two percent excise duty rollback. But concessions given to medical equipment, and exemptions of custom duty on inputs for manufacture of orthopedic implants should lead to a reduction in prices of these devices. Also, if certain parts are imported for manufacture of equipment in India, no CVD and SAD will be levied and only five percent basic customs duty will apply.


Gautam Khanna, Executive Director - Healthcare Business, 3M India comments, “A concession of basic duty on the manufacture of parts and accessories of medical equipments is a welcome move. Also, full exemption on medical equipments will help manufacturers make it available for end users at a better price.”


He further comments, “Increase in healthcare budget allocation is going to be a welcome change as it will help boost public health, insurance and infrastructure. This will hopefully see a potential increase in the penetration of health insurance in India and the move is expected to have a direct positive impact on the demand and quality of healthcare services in India.”


V Raja, President and CEO, GE Healthcare South Asia says, “While the budget is a very balanced one, we would have been happier if infrastructure status was granted to the healthcare industry. Healthcare industry is one of the largest and most critical one for healthy people, healthy country and a healthy economy. Infrastructure status would have helped healthcare industry to have access to more funds, more benefits and thus resulted in increased and affordable healthcare to the masses. “


Overall the industry was not really enthused with this years' budget and termed the steps announced not enough to give the necessary boost to the sector. The industry was also expecting an increase in healthcare infrastructure, with creation of focused SEZs and tax holiday on exports, which remained unaddressed.

Wednesday, February 24, 2010

Sex addiction - a disorder?

Psychiatrists are examining what is commonly referred to as sex addiction, a controversial and often misunderstood condition that has most recently garnered news media attention because of the travails of golfer Tiger Woods .




Sex addiction is not recognised by any official diagnosis in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM), considered the definitive word on psychological disorders, reports the Courier Mail .



However, the term 'hypersexual disorder' is being proposed for the fifth edition of DSM, due out in 2012.



The proposal is being put forward by Dr Martin Kafka, a clinical associate professor of psychiatry at Harvard Medical School, in the US, who says the disorder has been neglected for years.



He says it causes everything from marital dysfunction and divorce to increased risk of unintended pregnancies and sexually transmitted diseases.



To be diagnosed with the disorder a patient would have to meet four of the following five criteria:



• Spending a 'great deal of time' consumed by sexual fantasies and urges.

• Using sexual behaviour to deal with stressful life events (or anxiety, depression, boredom or irritability).

• Disregarding the 'physical and emotional harm' to those involved.

• Patients must have tried but failed to curb the behaviour.

• Patients must have suffered distress and harm to their everyday life.



However, the controversial proposal has critics worrying that the criteria are too vague, and the chances for misdiagnosis and bogus pharmaceutical treatment are too great.



Dr Paul Fedoroff, director of the Sexual Behaviours Clinic at the Royal Ottawa Mental Health Centre, is a critic of Kafka's hypersexuality criteria.



He questions whether sex in response to stress is unhealthy, and what is meant by 'a great deal of time' consumed by sexual fantasies.



But Dr Dan Zucker, of the University of Toronto, who heads a working group dealing with the next edition of DSM, expects 'hypersexuality disorder' to be listed.



He admits the proposal is controversial but says the issue is about where to draw the line on what is normal, and what is not.

Tuesday, February 23, 2010

Dalai Lama On Twitter

Watch out for tweets from no less than the Dalai Lama. The spiritual head of the Tibetan Buddhist community has joined the social networking website Twitter to keep in touch with followers.

"His Holiness the Dalai Lama has joined Twitter," said a post on the website of the Tibetan government-in-exile Tuesday.

The Dalai Lama had fled Tibet after a failed uprising against Chinese rule in 1959 and is now based in this Indian town. He was awarded the Nobel Peace Prize in 1989.

Around 140,000 Tibetans now live in exile, over 100,000 of them in different parts of India. Over six million Tibetans live in Tibet.

Monday, February 22, 2010

Buddha Shaped Pears

Gao Xianzhang has managed to create what some would call the holiest fruits ever, pears shaped like Buddha.


Gao has been working on his pear-growing technique for six years and this season he managed to grow 10,000 Buddha-shaped baby pears. Each fruit is grown in an intricate Buddha mould and ends up looking like a juicy figurine. The ingenious farmer says the locals in his home village of Hexia, norther China, have been buying his Buddha pears as soon as he picks them from the trees. Most of them think they are cute and that they bring good luck.



Gao Xianzhang pears aren’t cheap, roughly $1.8 each, but their success in China convinced him to start exporting them into Europe.
Professor Masayuki Sumida, Research Team @ Hiroshima University’s Institute for Amphibian Biology has created a transparent frog whose internal organs are visible through its skin.




The researchers say the see-through frogs can help in the study of diseases and in the development of medical treatments by allowing laboratory scientists to check the status of internal organs and blood vessels while the frogs are alive and without having to dissect them.




According to Sumida, the transparent frog is the result of breeding two specimens of Japanese brown frog (Rana japonica) that had a genetic mutation giving them pale skin. By selectively breeding their offspring, the researchers were able to create a frog that remains transparent for its entire life cycle.



Most of the world’s known transparent creatures live underwater, and transparent four-legged animals are extremely rare.



The researchers also say that by fusing the genes of fluorescent proteins to the frog’s genes, they can create frogs that glow. Glowing frogs can help scientists study specific “problem” genes by providing a real-time visual indication (i.e. the frogs glow) when those genes become active.



Professor Sumida says, “Transparent frogs will prove useful as laboratory animals because they make it easier and cheaper to observe the development and progress of cancer, the growth and aging of internal organs, and the effects of chemicals on organs.”



Very Interesting..............